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, 2008a), in addition to in Pompe illness through which the accumulation of enormous pools of autophagic debris is a typical and constant feature of skeletal muscle mass pathology (Fukuda et al(2017) A novel method of examine lysosomal dysfunctions by subcellular proteomics and lipidomics: the case of NPC1 deficiency. Sci Rep(2017) mTORC1 hyperacti